Table 3.
Results of linear mixed model analysis for the outcome measures participation, HRQoLa, fatigue, physical functioning, and psychological well-being in patients recovering from COVID-19 receiving primary allied health care in a Dutch prospective cohort study.
| General outcome measures | Baseline (T0), mean (SE) | 3 months (T1), mean (SE) | 6 months (T2), mean (SE) | At 3 months | At 6 months | ||||||||||||||
|
|
Estimate (95% CI) |
P value | Estimate (95% CI) |
P value | |||||||||||||||
| Participation | |||||||||||||||||||
|
|
USER-Pb frequencies subscale | 27.5 (0.3) | 30.5 (0.3) | 31.5 (0.3) | 2.9 (2.3 to 3.7) | <.001 | 3.9 (3.3 to 4.7) | <.001 | |||||||||||
|
|
USER-P restrictions subscale | 64.6 (0.6) | 73.7 (0.6) | 77.6 (0.6) | 9.1 (7.9 to 10.3) | <.001 | 13.0 (11.8 to 14.2) | <.001 | |||||||||||
|
|
USER-P satisfaction subscale | 48.7 (0.5) | 54.7 (0.6) | 58.4 (0.6) | 5.9 (4.8 to 7.2) | <.001 | 9.7 (8.5 to 10.9) | <.001 | |||||||||||
| HRQoL (EQ-VASc score) | 55.6 (0.5) | 64.6 (0.6) | 67.9 (0.7) | 9.0 (7.8 to 10.2) | <.001 | 12.3 (11.1 to 13.6) | <.001 | ||||||||||||
| Fatigue (FSSd score) | 5.6 (0.03) | 5.2 (0.04) | 4.9 (0.04) | –0.4 (–0.5 to –0.4) | <.001 | –0.7 (–0.8 to –0.6) | <.001 | ||||||||||||
| Physical functioning (PROMIS-PF-10be score) | 37.7 (0.2) | 41.6 (0.2) | 43.7 (0.2) | 3.9 (3.5 to 4.3) | <.001 | 5.9 (5.6 to 6.4) | <.001 | ||||||||||||
| Psychological well-beingf | |||||||||||||||||||
|
|
HADSg anxiety score | 7.1 (0.1) | N/Ah | 6.3 (0.1) | N/A | N/A | –0.8 (–1.0 to –0.5) | <.001 | |||||||||||
|
|
HADS depression score | 7.3 (0.1) | N/A | 5.7 (0.1) | N/A | N/A | –1.6 (–1.8 to –1.3) | <.001 | |||||||||||
aHRQoL: health-related quality of life.
bUSER-P: Utrecht Scale for Evaluation of Rehabilitation—Participation.
cEQ-VAS: EuroQol Visual Analog Scale.
dFSS: Fatigue Severity Scale.
ePROMIS-PF-10b: Patient-Reported Outcomes Measurement Information System Physical Functioning Short Form 10b.
fPsychological well-being was only assessed at baseline (T0) and at 6 months (T2).
gHADS: Hospital Anxiety and Depression Scale.
hN/A: not applicable.