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. 2023 Oct 20;9:e44155. doi: 10.2196/44155

Table 3.

Results of linear mixed model analysis for the outcome measures participation, HRQoLa, fatigue, physical functioning, and psychological well-being in patients recovering from COVID-19 receiving primary allied health care in a Dutch prospective cohort study.

General outcome measures Baseline (T0), mean (SE) 3 months (T1), mean (SE) 6 months (T2), mean (SE) At 3 months At 6 months

Estimate
(95% CI)
P value Estimate
(95% CI)
P value
Participation

USER-Pb frequencies subscale 27.5 (0.3) 30.5 (0.3) 31.5 (0.3) 2.9 (2.3 to 3.7) <.001 3.9 (3.3 to 4.7) <.001

USER-P restrictions subscale 64.6 (0.6) 73.7 (0.6) 77.6 (0.6) 9.1 (7.9 to 10.3) <.001 13.0 (11.8 to 14.2) <.001

USER-P satisfaction subscale 48.7 (0.5) 54.7 (0.6) 58.4 (0.6) 5.9 (4.8 to 7.2) <.001 9.7 (8.5 to 10.9) <.001
HRQoL (EQ-VASc score) 55.6 (0.5) 64.6 (0.6) 67.9 (0.7) 9.0 (7.8 to 10.2) <.001 12.3 (11.1 to 13.6) <.001
Fatigue (FSSd score) 5.6 (0.03) 5.2 (0.04) 4.9 (0.04) –0.4 (–0.5 to –0.4) <.001 –0.7 (–0.8 to –0.6) <.001
Physical functioning (PROMIS-PF-10be score) 37.7 (0.2) 41.6 (0.2) 43.7 (0.2) 3.9 (3.5 to 4.3) <.001 5.9 (5.6 to 6.4) <.001
Psychological well-beingf

HADSg anxiety score 7.1 (0.1) N/Ah 6.3 (0.1) N/A N/A –0.8 (–1.0 to –0.5) <.001

HADS depression score 7.3 (0.1) N/A 5.7 (0.1) N/A N/A –1.6 (–1.8 to –1.3) <.001

aHRQoL: health-related quality of life.

bUSER-P: Utrecht Scale for Evaluation of Rehabilitation—Participation.

cEQ-VAS: EuroQol Visual Analog Scale.

dFSS: Fatigue Severity Scale.

ePROMIS-PF-10b: Patient-Reported Outcomes Measurement Information System Physical Functioning Short Form 10b.

fPsychological well-being was only assessed at baseline (T0) and at 6 months (T2).

gHADS: Hospital Anxiety and Depression Scale.

hN/A: not applicable.