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. 2023 Oct 11;19(10):e1010905. doi: 10.1371/journal.pgen.1010905

Fig 3. Identification of early and late DEG patterns and heatmaps for top DEGs in each.

Fig 3

(a) DEGs for each paradigm were split into upregulated (red) and downregulated (blue) as well as early (16-32h) and late (48-72h) based on peaks in Fig 2. The distribution of DEGs in these 8 patterns is shown in terms of unique and shared DEGs across both cell types. (b-h) The top 25 genes are plotted in heatmaps as a function of the largest fold changes at the middle timepoint in each pattern (24h and 60h) to demonstrate top genes defining each 8 patterns (NTR-rod and NTR-bipolar for patterns early-up, early-down, late-up and late-down).