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. 2023 Aug 21;3:20. Originally published 2023 Apr 24. [Version 4] doi: 10.3310/nihropenres.13421.4

PMC10593357.1; 2023 Apr 24
PMC10593357.2; 2023 Jul 4
PMC10593357.3; 2023 Jul 20
PMC10593357.4; 2023 Aug 21

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Copyright: © 2023 Bretherick AD et al.

This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Associations of symptoms or age to 5 ME/CFS onset types: ( A) Fatigue symptoms (10 tests), ( B) Non-fatigue symptoms (74 tests), and ( C) Illness course descriptions (7 tests). These were considered in a logistic regression model of the form OnsetType ~ age + sex + symptoms/descriptions and an intercept. A covariate is only shown if it survived Bonferroni multiple testing correction ( p<0.05) per regression for one or more symptom/description. Significant associations are indicated with an asterisk (*); their Z-scores lie outside of non-significant values, bounded by the red dashed lines, after Bonferroni multiple testing correction. The z-score (Y-axis) is the effect-size estimate in standard deviation units.