Table 1.

Prevalence of FH variant carriers in the Million Veteran Program

	Ancestry group
	All	African	Asian	European	Hispanic	Unclassified
n	455,734	87,163	4,553	318,694	34,151	11,173
FH variant carriers	1,504	258	11	1,095*	111	29
LDLR LoF	165	20	3	130	10	2
LDLR missense	944	222	6	606	91	19
APOB	383	16	2	349	8	8
PCSK9	13	0	0	11	2	0
Prevalence	1:303	1:338	1:414	1:291	1:308	1:385
(95% CI)	(1:288–319)	(1:301–385)	(1:260–1,010)	(1:275–309)	(1:259–378)	(1:283–605)

^*One individual was found to be a carrier of both an LDLR missense variant and an APOB variant.

LoF = loss of function. CI = confidence interval.