Table 2.
Prevalence of FH variant carriers by LDL-C level, defined by the first available, the maximum observed, or the mean of all measures.
| LDL-C (mg/dL) | n | FH variant carriers (%) |
|---|---|---|
|
| ||
| First | ||
| ≤130 | 264,734 | 640 (0.2) |
| 131–190 | 135,800 | 535 (0.4) |
| >190 | 18,256 | 252 (1.4) |
| >250 | 1,816 | 70 (3.9) |
| Maximum | ||
| ≤130 | 124,964 | 236 (0.2) |
| 131–190 | 191,581 | 500 (0.3) |
| >190 | 102,245 | 691 (0.7) |
| >250 | 24,089 | 321 (1.3) |
| Mean | ||
| ≤130 | 293,585 | 642 (0.2) |
| 131–190 | 119,689 | 607 (0.5) |
| >190 | 5,516 | 178 (3.2) |
| >250 | 244 | 28 (11.5) |
To convert LDL-C values from mg/dL to mmol/L, divide by 38.67.
LDL-C = low-density lipoprotein cholesterol
FH = familial hypercholesterolemia