Table 1.
Region-Specific Quantification of tdTomato+ Neurons in Male Postnatal Day 14 TRAP2 Mice TRAPed During Normal Rearing or Adverse Rearing Conditions
| Brain Region | Control TRAPed Neurons | ELA TRAPed Neurons | p Value |
|---|---|---|---|
| Paraventricular Thalamus | |||
| Anterior | 79.31 [60.74, 97.88] | 133.60 [116.80, 150.40] | .0001 |
| Mid | 39.33 [31.39, 47.27] | 57.65 [46.73, 68.57] | .008 |
| Posterior | 80.31 [59.56, 101.06] | 145.10 [109.70, 180.50] | .005 |
| Nucleus Accumbens | |||
| Core | 9.16 [6.67, 11.65] | 7.76 [5.18, 10.34] | .397 |
| Medial shell | 1.73 [1.08, 2.38] | 1.63 [0.90, 2.36] | .823 |
| Amygdala | |||
| Basolateral | 17.00 [13.01, 20.99] | 13.61 [8.37, 18.85] | .278 |
| Central | 11.29 [5.11, 17.47] | 8.90 [2.59, 15.21] | .556 |
| Medial Prefrontal Cortex | |||
| Prelimbic | 5.29 [4.26, 6.32] | 6.88 [1.64, 12.12] | .521 |
| Infralimbic | 7.13 [3.49, 10.77] | 6.14 [3.19, 9.09] | .631 |
| Ventral tegmental area | 4.80 [2.26, 7.34] | 6.11 [2.26, 9.96] | .516 |
| Hypothalamus | |||
| Suprachiasmatic | 56.00 [46.56, 65.44] | 65.57 [54.76, 76.38] | .137 |
| Paraventricular | 21.67 [13.75, 29.59] | 25.58 [16.24, 34.92] | .489 |
| Lateral | 12.14 [5.11, 19.17] | 10.43 [4.96, 15.90] | .646 |
| Ventromedial | 6.71 [2.65, 10.77] | 3.43 [0.82, 6.04] | .121 |
| Hippocampus | |||
| CA1 | 14.33 [8.64, 20.02] | 11.75 [8.80, 14.70] | .301 |
| CA3 | 10.17 [6.69, 13.65] | 10.38 [6.56, 14.2] | .926 |
| Dentate gyrus | 20.50 [10.53, 30.47] | 19.13 [2.20, 26.06] | .778 |
Values are presented as mean [95% confidence interval lower limit, 95% confidence interval upper limit].
ELA, early-life adversity; TRAP, targeted recombination in active populations.