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. 2023 Oct 24;4(6):e413. doi: 10.1002/mco2.413

FIGURE 2.

FIGURE 2

Milestones in the development of imaging techniques used in EAT‐related research. In 2001, Taguchi et al. first proposed a CT‐based measurement of EAT volume. In 2003, Iacobellis et al. first proposed using echocardiography to measure EAT thickness. Around 2015, algorithms for fully automated EAT segmentation and quantification emerged. In 2017, Antonopoulos et al. first proposed fat attenuation index of EAT as a novel imaging biomarker. In 2019, Oikonomou et al. first applied radiomics for analyzing EAT.