Table 2.
Demographic data of subjects with CADASIL.
Number of People (N = 30) | Female | N = 20 | Male | N = 10 | |
---|---|---|---|---|---|
Age | 43.6 ± 11.5 | 39.6 ± 15.8 | |||
Age of CADASIL diagnosis |
≤45 years old >45 years old |
11 9 |
≤45 years old >45 years old |
5 5 |
|
Headache | Yes | 20 | Yes | 9 | |
MA | Yes | 10 | Yes | 4 | |
MO | Yes | 3 | Yes | 0 | |
Other types of headaches (N = 12) | TTH (N = 2) | Yes | 1 | Yes | 1 |
Headache (N = 10) | Yes | 6 | Yes | 4 | |
Family history of headache | Yes | 11 | Yes | 4 | |
Genetic tests of NOTCH3 |
Yes | 20 | Yes | 10 | |
Stroke in family history | Yes | 2 | Yes | 1 | |
Neuroimaging changes (MRI/CT) | Vascular changes/ischemic stroke | 8 | Vascular changes/ischemic stroke | 2 |
N—number of people, F—female, M—male, MA—migraine with aura, MO—migraine without aura, TTH—tension-type headache, MRI—magnetic resonance imaging, CT—computed tomography.