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. 2005 Mar 3;115(4):860–869. doi: 10.1172/JCI200523640

Figure 2.

Figure 2

Cytokine secretion during Con A–induced hepatitis. Cytokine levels in the serum after Con A injection in wild-type (gp130LoxP/LoxP) and alfpCre gp130LoxP/LoxP mice. Three hours before Con A administration, animals were treated with NaCl (solid line) or IL-6 (200 μg/kg) (dotted line) by i.p. injection. (A and B) TNF-α levels of wild-type and alfpCre gp130LoxP/LoxP mice. #P < 0.01 vs. corresponding IL-6–pretreated wild-type control group at the same time point. (C and D) IFN-γ levels of wild-type and alfpCre gp130LoxP/LoxP mice. (E and F) IL-6 concentrations of wild-type and alfpCre gp130LoxP/LoxP mice. §P < 0.001 and #P < 0.01 vs. corresponding IL-6–pretreated wild-type or alfpCre gp130LoxP/LoxP mice at the same time point.