Figure 5.

Effect of B. coagulans administration on gut microbiota profile and enterobacterial genera with significant differences detected in relative abundance ratios. Stacked bar graphs show the relative abundance of each bacterial genus in the intestinal flora (A). The 20 genera with the highest average relative abundance of all samples were color-coded, and the other bacterial genera were labeled as “Others”. Mouse numbers are indicated below the stacked bar graphs. We compared the relative abundance ratios of enterobacteria between the control group and the B. coagulans intake group (Wilcoxon rank sum test) (B). In addition, the bacterial family in (B) is included in “Others” in (A). (B) Shows the results for all mice including male and female. C, control group; L, B. coagulans intake group. The values are presented as mean ± SD of three animals. Significant differences were observed between C and L in all parameters (p < 0.05).