TABLE 1.

Putative roles for creatine in brain health

Putative role for creatine in brain health	References
Phosphate carrier	Wyss et al. [12]
	Hemmer et al. [14]
	Bonvento et al. [32]
	Bessman et al. [33]
ROS scavenging properties	Tarafdar et al. [73]
	Lawler et al. [74]
	Sestil et al. [75]
	Sestill et al. [76]
	Stachowiak et al. [79]
Improved energy metabolism	Snow et al. [26]
	Snow et al. [27]
	Brewer et al. [28]
	Snow et al. [80]
Protection against inflammation	Snow et al. [26]
	Snow et al. [80]
Modulation of AD neuropathology	Snow et al. [26]
	Snow et al. [27]
	Brewer et al. [28]
mTORC1 signaling	Mao et al. [54]
	Pazini et al. [84]

AD, Alzheimer's Disease; ROS, reactive oxygen species.