Kilickan 2008 (A).

Study characteristics
Methods	Randomised controlled trial Run‐in period: not specified Number of centres and location: not specified
Participants	A total of 39 participants were included in part A of this study. Inclusion criteria: patients undergoing elective CABG with CPB Exclusion criteria: LVEF < 40%, diabetes, active gastropathic disorder; preoperative use of steroids and contraindication to steroid administration, contraindication to epidurals, systemic or local infection, preoperative signs of infection, chronic inflammatory disease, treatment with COX inhibitors, drugs inhibiting thrombocyte function within 7 days of operation
Interventions	Intervention: 6‐methylprednisolone 15 mg/kg intravenously 60 min before induction Control: conventional management
Outcomes	IL‐10, glucose, clinical outcomes
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	No details given
Allocation concealment (selection bias)	Unclear risk	No details given
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	No details given
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	No details given
Incomplete outcome data (attrition bias) All outcomes	Low risk	All data included in analysis
Selective reporting (reporting bias)	Low risk	No reporting bias apparent
Other bias	Unclear risk	No details given