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. 2023 Oct 24;2023(10):CD014967. doi: 10.1002/14651858.CD014967.pub2

Comparison 3. Phenobarbital versus phenytoin as first‐line ASM in EEG‐confirmed neonatal seizures.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
3.1 Proportion of infants who achieve seizure control after the maximal loading dose of ASM 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
3.2 Arrythmias causing circulatory disturbance 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
3.3 Hypotension requiring volume or inotropes 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
3.4 Bradycardia 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected