NCT04320940.

Study name	Efficacy and safety of intravenous phenobarbital in neonatal seizures
Methods	RCT, double‐blind
Participants	Neonates > 33 weeks with high probability of seizures, cEEG, seizures for at least 30 s/h
Interventions	PB 20/kg (if required plus 20) vs PB 40 mg/kg (if required plus 10)
Outcomes	No requirement of ASM after 1st dose PB at 24 hours; no requirement of ASM after 1st dose PB at 2 hours; no requirement of ASM after 2nd dose of PB; seizure burden
Starting date	2020
Contact information	rnoor@nemaresearch.net
Notes	Calculated sample size 490; very interesting study