Comparison 3. Indicated prevention intervention versus control group in preventing mental disorders in adults.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
3.1 Diagnosis of mental disorders at 0‐1 months	3	843	Risk Ratio (M‐H, Random, 95% CI)	0.30 [0.06, 1.57]
3.2 Diagnosis of mental disorders at 1‐6 months	6	1352	Risk Ratio (M‐H, Random, 95% CI)	0.65 [0.50, 0.84]
3.3 Diagnosis of mental disorders at 7‐24 months	2	380	Risk Ratio (M‐H, Random, 95% CI)	0.69 [0.41, 1.19]
3.4 Quality of life at 0‐1 months	8	1136	Std. Mean Difference (IV, Random, 95% CI)	‐0.36 [‐0.61, ‐0.12]
3.5 Quality of life at 1‐6 months	4	847	Std. Mean Difference (IV, Random, 95% CI)	‐0.04 [‐0.23, 0.16]
3.6 Quality of life at 7‐24 months	1	94	Mean Difference (IV, Random, 95% CI)	‐0.80 [‐3.53, 1.93]
3.7 Adverse events at 0‐1 months	1	547	Risk Ratio (M‐H, Random, 95% CI)	Not estimable
3.8 Psychological functioning and impairment at 0‐1 months	4	663	Std. Mean Difference (IV, Random, 95% CI)	‐0.12 [‐0.39, 0.15]
3.9 Psychological functioning and impairment at 1‐6 months	2	594	Std. Mean Difference (IV, Random, 95% CI)	‐0.10 [‐0.60, 0.41]
3.10 Psychological functioning and impairment at 7‐24 months	2	241	Std. Mean Difference (IV, Random, 95% CI)	‐0.21 [‐0.47, 0.04]
3.11 Depressive symptoms at 0‐1 months	18	2341	Std. Mean Difference (IV, Random, 95% CI)	‐0.16 [‐0.30, ‐0.03]
3.12 Depressive symptoms at 1‐6 months	11	2609	Std. Mean Difference (IV, Random, 95% CI)	‐0.34 [‐0.58, ‐0.10]
3.13 Depressive symptoms at 7‐24 months	8	2149	Std. Mean Difference (IV, Random, 95% CI)	‐0.10 [‐0.22, 0.01]
3.14 Anxiety symptoms at 0‐1 months	5	250	Std. Mean Difference (IV, Random, 95% CI)	‐1.19 [‐2.02, ‐0.35]
3.15 Anxiety symptoms at 1‐6 months	4	771	Std. Mean Difference (IV, Fixed, 95% CI)	‐0.23 [‐0.37, ‐0.09]
3.16 Anxiety symptoms at 7‐24 months	2	549	Std. Mean Difference (IV, Fixed, 95% CI)	‐0.12 [‐0.29, 0.05]
3.17 Distress/PTSD symptoms at 0‐1 months	19	2536	Std. Mean Difference (IV, Random, 95% CI)	‐0.54 [‐0.95, ‐0.14]
3.18 Distress/PTSD symptoms at 1‐6 months	9	1702	Std. Mean Difference (IV, Random, 95% CI)	‐0.29 [‐0.51, ‐0.07]
3.19 Distress/PTSD symptoms at 7‐24 months	5	1081	Std. Mean Difference (IV, Random, 95% CI)	‐0.04 [‐0.45, 0.38]
3.20 Social outcomes at 0‐1 months	5	932	Std. Mean Difference (IV, Random, 95% CI)	‐0.08 [‐0.26, 0.09]
3.21 Social outcomes at 7‐24 months	1	241	Mean Difference (IV, Random, 95% CI)	‐0.19 [‐1.88, 1.50]