Willis 2019.

Study characteristics
Methods	Study design: RCT Duration of study: the study was conducted between December 2014 and November 2015. Country: Midlands province, Zimbabwe Income classification: low‐income country from 2014 to 2015 Geographical scope: rural Healthcare setting: primary care facility (3 clinics: 2 in the intervention group and 1 in the control group)
Participants	1. Age: 10‐15 years; majority aged 10 years 2. Gender: both 3. Socioeconomic background: not specified 4. Educational background: among those attending, most were in primary school. Inclusion criteria: a. HIV‐positive adolescents; b. 10‐15 years old; c. ART—aware of their HIV status; d. accessing ART at the study clinic; e. consent from caregiver; f. assent from adolescent. Exclusion criteria: a. unaware of HIV status; b. nonconsent from caregiver; c. nonassent from adolescent. Note: at baseline, the intervention and control group scores for quality of life were, respectively, 3.16 and 3.61. Stated purpose: to determine the effectiveness of Community Adolescent Treatment Supporters (CATS) services on improving linkage to services and retention in care, adherence and psychosocial well‐being among 100 adolescents living with HIV (ALHIV) in a rural district of Zimbabwe
Interventions	Name: CATS services Title/name of PW and number: 9 CATS 1. Selection: 18‐24 years old living with HIV 2. Educational background: not specified 3. Training: PWs trained by Ministry of Health and Child Care (MoHCC) 4. Supervision: all nine CATS attended a weekly feedback meeting at the clinic by CATS mentor. 5. Incentives/remuneration: not specified Prevention type: selective—participants were included based upon the presence of a risk factor (living with HIV). Intervention details: participants in the intervention arm received the same standard of care but were also allocated to one CATS for additional support for 12 months. This included a weekly home visit during which the allocated CATS provided HIV and ART information and counselling as well as monitored the participants’ adherence and general well‐being. In the event that the participant was unwell or faced difficulties with adherence, the CATS would refer the participant to the CATS mentor in their district. The mentor would then liaise with the participants’ clinic for follow‐up. CATS additionally supported caregivers with information and counselling. Control: usual care – standard of care provided by the MoHCC, including monthly clinic reviews, ART, adherence counselling, CD4 monitoring and management of opportunistic infections. Treatment and care was led by a nurse and/or a primary counsellor.
Outcomes	Participants’outcomes of interest for this review Nil Carers’ outcomes of interest for this review Nil Economic outcomes Nil Time points: baseline, post‐intervention (< 1 month) Note: data were not included in the meta‐analysis because they were not provided in the right format or were not available even after attempted author contact.
Notes	Source of funding: Bristol‐Myers Squibb Foundation (BMSF). P.M. from BMSF also contributed as an author of the final manuscript. Notes on validation of instruments (screening and outcomes): the questionnaire was created ad hoc for the study. Additional information: none Handling the data: the data are not publicly available but can be obtained from the corresponding author (NW). No permissions are needed to obtain the data. Prospective trial registration number: PACTR201711002755428