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. 2023 Oct 24;2023(10):CD014722. doi: 10.1002/14651858.CD014722.pub2

NCT03231358.

Study name Our Family Our Future: a resilience‐oriented family intervention to prevent adolescent HIV/STI infection and depression in South Africa
Methods Study design: RCT
Country: South Africa
Participants Adolescents (14‐16 years) and their parents
Inclusion criteria: 
a. 14‐16 years;
b. adolescent concurs that the adult identified is their parent (to also include primary caregivers in the parental role);
c. when more than one child in the family falls within the eligible age range, one child will be chosen at random;
d. lives in the household at least 4 days a week.
Exclusion criteria:
a. no or low symptoms (< 6) or clinically significant thresholds of depression (16+)
Stated purpose: to test the efficacy of Our Family Our Future, an integrated intervention for preventing HIV and depression onset amongst adolescents
Interventions Intervention:
Our Family Our Future
Our Family Our Future is a 'selective' behavioural prevention programme, designed to address HIV/STI acquisition, sexual risk behaviour, and depression amongst adolescents (ages 14‐16) in communities with high HIV prevalence and from families where adolescents and parents already exhibit mild, potentially troublesome, depressive symptoms but do not reach the threshold for further screening for a significant clinical depressive disorder. This intervention involves parent‐child dyads who receive the intervention in a community setting, in a facilitated group format. The intervention consists of 3‐hour sessions, held weekly for 3 consecutive weeks with an individual family meeting in the third or fourth week depending on family desires.
Control:
Usual care (consisting of a packet of existing available brochures on HIV, STIs, mental health including places to access care)
Outcomes Participants'outcomes of interest for this review
  1. Mental health symptoms/depression – Center for Epidemiologic Studies Depression Scale ‐ Child Version (CES‐DC)

  2. Social outcomes (social support) – Multidimensional Scale of Perceived Social Support (MSPSS)

  3. Mental health symptoms/(parental) depression ‐ Center for Epidemiologic Studies Depression Scale (CES‐D)


Economic outcomes
Nil
Time points: baseline, post‐intervention (12 months)
Starting date 21 November 2018
Contact information Caroline Kuo, caroline_kuo@brown.edu
Notes Source of funding: no clear specification for funding
Prospective trial registration number: NCT03231358