Table 4.
Logistic regression analysis of risk factors associated with poor 30-day outcomes in SAP patients
| Risk factor | Univariate analysis | Multivariate analysis* | Multivariate analysis# | ||||||
|---|---|---|---|---|---|---|---|---|---|
| OR(95% CI) | P value | Model 1 OR(95% CI) | P value | Model 2 OR(95% CI) | P value | ||||
| P1 | |||||||||
| p__Actinobacteriota | 25.837(1.367-488.456) | 0.030 | 22.954(1.376-383.026) | 0.029 | 24.270(1.338-440.331) | 0.031 | |||
| c__Actinobacteria | 11.632(1.163-116.352) | 0.037 | 12.932(1.316-127.104) | 0.028 | 13.061(1.178-144.754) | 0.036 | |||
| o__Actinomycetales | 50.309(1.881-1345.855) | 0.019 | 22.372(1.075-465.609) | 0.045 | 63.506(1.643-2454.396) | 0.026 | |||
| f__Actinomycetaceae | 51.187(2.054-1275.877) | 0.016 | 23.662(1.190-470.657) | 0.038 | 62.317(1.721-2256.818) | 0.024 | |||
| g__Actinomyces | 5.162(1.049–25.411) | 0.044 | NA | NA | NA | NA | |||
| P2 | |||||||||
| p__Actinobacteriota | 9.773(1.230-77.633) | 0.031 | NA | NA | 119.502(1.283-11133.762) | 0.039 | |||
| c__Actinobacteria | 5.845(1.013–33.727) | 0.048 | NA | NA | NA | NA | |||
| Δ | |||||||||
| f__Actinomycetaceae | 0.148(0.023–0.967) | 0.046 | NA | NA | 0.043(0.002–0.865) | 0.040 | |||
| g__Actinomyces | 0.143(0.021–0.987) | 0.048 | NA | NA | 0.055(0.003–0.974) | 0.048 | |||
* Model 1 adjusted by SOFA, APACHE II, initial GCS score and length of ICU stay
# Model 2 adjusted by age, initial NIHSS score, enteral nutrition, atrial fibrillation, dysphagia, and NLR (neutrophil to lymphocyte ratio)
P1 = log-transformed average (before diagnosis of SAP samples); P2 = log-transformed average (after diagnosis of SAP samples); Δ = P2-P1.