Table 1.
Characteristics of patients at baseline
| Interventional cohort | Observational cohort | P-value | |||
|---|---|---|---|---|---|
| N | Median (IQR) or n (%) | N | Mean (95% CI) or n (%) | ||
| Age [years] | 98 | 61 (49, 71) | 203 | 66 (56, 77) | < 0.001 |
| Sex | 98 | 203 | |||
| Female | 29 (29.6%) | 86 (42.4%) | 0.03 | ||
| Male | 69 (70.4%) | 117 (57.6%) | |||
| Body weight [kg] | 96 | 80 (74, 90) | 163 | 76 (68, 85) | 0.004 |
| Height [m]a | 91 | 1.72 (1.70, 1.74) | 150 | 1.69 (1.68, 1.71) | 0.02 |
| BMI [kg/m2]a | 91 | 27.1 (25.3, 30.8) | 148 | 26.3 (24.2, 28.6) | 0.005 |
| Charlson index | 97 | 2 (1, 3) | 203 | 3 (1, 5) | < 0.001 |
| Diabetes mellitus | 98 | 13 (13.3%) | 203 | 35 (17.2%) | 0.41 |
| COPD | 98 | 5 (5.1%) | 203 | 23 (11.3%) | 0.09 |
| Obesity | 98 | 25 (25.5%) | 180 | 29 (16.1%) | 0.08 |
| Hypertension | 96 | 36 (37.5%) | 203 | 114 (56.2%) | 0.003 |
| Smoking | 96 | 5 (5.2%) | 203 | 9 (4.4%) | 0.77 |
| Vaping cigarettes user | 5 | 1 (20.0%) | 7 | 0 (0.0%) | 0.42 |
| Alcoholism | 96 | 3 (3.1%) | 203 | 2 (1.0%) | 0.33 |
| Active opioid use | 96 | 1 (1.0%) | 203 | 0 (0.0%) | 0.32 |
| Haemodialysis | 96 | 0 (0.0%) | 203 | 0 (0.0%) | n/a |
| Immunocompromised | 97 | 0 (0.0%) | 203 | 7 (3.4%) | 0.10 |
Bold: values used in Propensity Score Matching
aMean and 95% CI are reported and p-value was obtained from t-test for independent samples