Table 2.
Weighted linear regression coefficients (β) and 95% confidence intervals for the association between sleep duration and SII and inflammatory markers: The United States, 2005 to 2008
| Exposure | Outcome | Categories | Model 1a β (95% CI), P- value |
Model 2b β (95% CI), P- value |
Model 3c β (95% CI), P- value |
|---|---|---|---|---|---|
| Sleep duration | SII | 7–9 h/night | Reference | Reference | Reference |
| < 7 h/night |
0.038(-16.479, 16.555) P = 0.996 |
12.165(-4.594, 28.925) P = 0.147 |
1.229(-17.940, 20.399) P = 0.884 |
||
| > 9 h/night |
54.748(-0.861,110.357) P = 0.053 |
52.542(-0.858,105.941) P = 0.053 |
35.656(-29.280,100.592) P = 0.235 |
||
| PLR | 7–9 h/night | Reference | Reference | Reference | |
| < 7 h/night |
-5.311(-8.397,-2.224) P = 0.001 |
-4.848(-8.074,-1.622) P = 0.005 |
-3.227(-6.918, 0.465) P = 0.078 |
||
| > 9 h/night |
5.694(-3.956,15.344) P = 0.237 |
3.817(-6.155,13.788) P = 0.437 |
5.426(-6.092, 16.944) P = 0.302 |
||
| NLR | 7–9 h/night | Reference | Reference | Reference | |
| < 7 h/night |
-0.038(-0.085,0.010) P = 0.115 |
0.003(-0.045,0.050) P = 0.913 |
-0.024(-0.077, 0.029) P = 0.321 |
||
| > 9 h/night |
0.145(0.003,0.288) P = 0.046 |
0.161(0.028,0.295) P = 0.020 |
0.089(-0.072, 0.251) P = 0.232 |
Abbreviation: CI Confidence interval, SII Systemic immune-inflammation index, PLR Platelet-to-lymphocyte ratio, NLR Neutrophil-to-lymphocyte ratio
Bold fonts indicate P value < 0.05
aModel 1: Unadjusted
bModel 2: Adjusted for age, sex, and race
cModel 3: Adjusted for age, sex, race, education level, PIR, BMI, smoking status, alcohol consumption status, recreational activities, hypertension, diabetes, CVD and taking immunosuppressants