Table 2.
Other factors for survival outcomes
| Factors | PFS | OS | ||||||
|---|---|---|---|---|---|---|---|---|
| HR (95%CI) | p value | Heterogeneity | HR (95%CI) | p value | Heterogeneity | |||
| I2 | Q test p value | I2 | Q test p value | |||||
| Gender | ||||||||
| M vs. F | 1.014 (0.929–1.107) | 0.753 | 41.7% | 0.127 | 1.041 (0.928–1.168) | 0.489 | 0.0% | 0.525 |
| Smoking history | ||||||||
| Smoker vs. no | 0.719 (0.645–0.802) | <0.001 | 49.4% | 0.065 | 0.894 (0.771–1.037) | 0.138 | 49.5% | 0.095 |
| ECOG | ||||||||
| <2 vs. ≥2 | 0.630 (0.482–0.822) | 0.001 | 81.1% | <0.001 | 0.498 (0.372–0.667) | <0.001 | 81.0% | 0.001 |
| PD-L1 | ||||||||
| 1–49% vs. ≥50% | 0.817 (0.599–1.114) | 0.201 | 62.7% | 0.045 | 2.021 (0.908–4.495) | 0.085 | 80.9% | 0.022 |
| Histology | ||||||||
| Non-squa vs. squa | 0.873 (0.777–0.980) | 0.022 | 0.0% | 0.412 | 0.822 (0.705–0.959) | 0.013 | 17.4% | 0.271 |
Abbreviations: PFS, Progression-Free-Survival; OS, Overall-Survival; M, male; F, Female; PD-L1, Programmed Death 1; squa, squamous; Non-squa, Non-squamous