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. 2023 Oct 24;15:209. doi: 10.1186/s13098-023-01190-y

Table 2.

Experimented with details of the 26 studies selected in the review

TRE Regimen Study Design Study[Ref.](Year) Sample size(TRE/CON) Geographic region participants Study duration Weight(kg) TRE/CON Age(year) TRE/CON Sex (men/women) TRE/CON
16:8 RCT Kord-Varkaneh H et al.(2022) [43] 22/23 USA non-alcoholic fatty liver disease 12 weeks 83.75 ± 12.71/89.33 ± 18.47 41.36 ± 10.5 /44.17 ± 4.9 12(10)/15(8)
16:8 RCT Moro T et al. (2021) [44] 10/10 ITALY healthy adults 12 months 83.22 ± 5.92/84.64 ± 5.76
16:8 RCT Kotarsky C J et al.(2021) [45] 11/10 USA overweight and obese adults 8 weeks 82 ± 3/83 ±3 83 ± 3/82 ± 3
16:8 RCT He M et al.(2022) [46] 44/47 China visceral fat 3 months 84.3 ± 2.2/84.7 ± 2.0 43.0 ± 1.4/41.3 ± 1.4 30(14)/35(12)
16:8 PRE–POST randomized design Brady A J et al. (2021) [47] 12/11 IRELAND male Middle- and Long-Distance Runners 8 weeks 73.13 ± 6.06/72.17 ± 6.68 35.9 ± 8.6/39.9 ± 3.0
16:8 RCT Queiroz J.D.N et al. (2022) [11] 13/13 Brazil adults with overweight and obesity 8 weeks 83·4 ± 10·6/81·4 ± 13·1 26 ± 4/33 ± 6 2(11)/2(11)
16:8 RCT Chow L S et al. (2020) [24] 11/9 USA humans who are Overweight 12 weeks 95.2 ± 22.6/100.9 ± 28.1 46.5 ± 12.4/44.2 ± 12.3 2(9)/1(8)
16:8 RCT Lin Y J et al. (2021) [48] 30/33 Taiwan middle-aged women 8 weeks 65.9 ± 9.7/65.8 ± 8.8 50.1 ± 7.5/54.2 ± 7.9
16:8 RCT Moro T et al.(2020) [14] 8/8 Italy elite cyclists 4 weeks 67.04 ± 5.03/72.27 ± 6.24 19.38 ± 2.39/19.38 ± 1.60
16:8 RCT Cai H et al.(2019) [49] 95/79 China non-alcoholic fatty liver disease 12 weeks 74.98 ± 8.02/72.94 ± 8.00 33.56 ± 6.23/34.5 ± 6.96 60(35)/66(13)
16:8 RCT Tinsley G M et al. (2019) [16] 8/9 Italy active females 8 weeks 63.8 ± 8.5/64.6 ± 8.8 23.3 ± 1.5/22.6 ± 2.7
16:8 RCT Lowe D A et al.(2020) [50] 59/57 USA adults with Overweight and Obesity 12 weeks 99.3 ± 16.9/99.1 ± 15.1 46.8 ± 10.8/46.1 ± 10.3 35(24)/35(22)
16:8 RCT Jamshed H et al. (2022) [51] 45/45 USA adults With Obesity 14 weeks 112.3 ± 20.1/105.3 ± 20.7 43 ± 11/43 ± 10

8(37)

10(35)

16:8 RCT Liu D et al. (2022) [41] 69/70 China obesity 12 months 31.6 ± 9.3/32.2 ± 8.8
16:8 RCT Xie Z et al.(2022) [40] 26/28 China healthy volunteers without obesity 5 weeks 61.1 ± 8.8/61.2 ± 9.9 28.68 ± 9.707/33.57 ± 11.6 9(17)/4(24)
16:8 RCT Bei-ni Lao et al.(2023) [52] 13/14 China overweight and obese patients with chronic kidney disease stages 3–4 12 weeks 51.8 ± 7.7/52.5 ± 11.3 51.8 ± 7.7/52.5 ± 11.3 7(6)/7(7)
14:10 RCT Haganes K L et al.(2022) [53] 33/33 Norway women with overweight/obesity 7 weeks 91.0 ± 10.8/95.0 ± 11.2 36.2*5.9/36.4*6.2
14:10 RCT Manoogian E et al.(2022) [54] 70/67 USA 24-h shift workers 12 weeks 108.07 ± 1.75/107.1 ± 5.35 41.07 ± 8.71/39.61 ± 9.39 65(5)/60(7)
14:10 RCT Che T et al.(2021) [17] 54/50 China overweight patients with type 2 diabetes 12 weeks 75.06 ± 4.42/74.68 ± 4.35 48.21 ± 9.32/48.78 ± 9.56 25(29)/24(26)
14:10 Randomized crossover trial Andriessen C et al.(2022) [55] 7/7 Netherlands adults with type 2 diabetes but does not improve insulin sensitivity 3 weeks 67.5 ± 5.2/66.9 ± 5.1 7(0)/7(0)
14:10 RCT Thomas E A et al.(2021) [56] 32/31 USA adults with obesity 39 weeks 96.1 ± 18.1/93.4 ± 18.4 38.3 ± 7.9/37.8 ± 7.8 7(35)/5(31)
12:12 RCT Phillips N.E et al.(2021) [57] 25/20 Switzerland community-Based Adults 6 months 79.6 ± 15.9/77.5 ± 13.8
12:12 RCT de Oliveira M P I et al.(2021) [11] 31/27 Brasil low-income women with obesity 12-months 81.25 ± 13.51/80.25 ± 9.40
21:3 RCT Rona A et al.(2018) [58] 7/6 UK free-living human 10 weeks 86.2 ± 5.2/77.8 ± 7.6 47 ± 3/45 ± 4 1(6)/0(6)

20:4

18:6

RCT Cienfuegos S et al.(2020) [18]

19/19

20/19

USA adults with obesity 8 weeks

100 ± 4/94 ± 3

99 ± 4/94 ± 3

47 ± 2/45 ± 2

47 ± 3/45 ± 2

2(17)/2(17)

3(17)/2(17)

18:6 RCT Mayra S T et al.(2022) [59] 8/10 USA college students 4 weeks 68.3 ± 11.3/67.6 ± 10.6 25.1 ± 4.1/21.8 ± 3.8 1(7)/2(8)
18:6 RCT Sutton E F et al(2018) [25] 5/7 USA men with Prediabetes 5weeks