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Chemical exchange saturation transfer (CEST) for differentiation of tumor progression versus radiation necrosis: examples of radiation necrosis (A) and tumor progression (B) are shown for patients with brain metastases following stereotactic radiosurgery. Examples of glioma are shown following chemoradiation, including an oligodendroglioma with radiation necrosis (C) and a progressed grade 3 astrocytoma (D). All images are of selected slices from the 3D CEST acquisition at 3T.
