TABLE 2.
Photopharmacology
| Type | Receptor/Effect | Source |
|---|---|---|
| Caged | Glutamate/agonist | (Callaway and Katz, 1993) (Ellis-Davies, 2007) |
| Caged | Adrenergic/agonists | (Muralidharan and Nerbonne, 1995) |
| Caged | GABA/agonist | (Gee et al., 1994) |
| Caged | μ- and λ-opioid/agonists | (Banghart and Sabatini, 2012) (Banghart et al., 2018) |
| Caged | D1R and D2R/agonists and antagonists | (Araya et al., 2013) (Gienger et al., 2020) |
| Caged | mGluR5/NAM | (Font et al., 2017) |
| Diffusible photoswitchable | mAChR M1-5/antagonist | (Nargeot et al., 1982) |
| Diffusible photoswitchable | mGluR5/NAM | (Pittolo et al., 2014) |
| Diffusible photoswitchable | A2A/partial agonist | (Bahamonde et al., 2014) |
| Diffusible photoswitchable | μ-opioid/agonist | (Schönberger and Trauner, 2014) |
| Diffusible photoswitchable | mGluR5/NAM | (Pittolo et al., 2014) |
| Diffusible photoswitchable | GLP-1/agonist | (Broichhagen et al., 2015b, 2016) |
| Diffusible photoswitchable | mGluR4/NAM and PAM | (Rovira et al., 2016) |
| Diffusible photoswitchable | mAChR M1/agonist | (Agnetta et al., 2017) |
| Diffusible photoswitchable | GPR40/ agonist | (Frank et al., 2017) |
| Diffusible photoswitchable | D1R and D2R/agonist | (Lachmann et al., 2017) |
| Diffusible photoswitchable | CB1/agonist | (Westphal et al., 2017) |
| Diffusible photoswitchable | CXCR3/agonist and antagonist | (Gómez-Santacana et al., 2018, 2019) |
| Diffusible photoswitchable | Histamine H3/agonist | (Hauwert et al., 2018) |
| Diffusible photoswitchable | CB2/agonist | (Sarott et al., 2021) |
| Diffusible photoswitchable | mGluR2/PAM | (Donthamsetti et al., 2021a) |
| Diffusible photoswitchable | 5HT2A/agonist | (Gerwe et al., 2022) |
| Tethered photoswitchable | mAChR/agonist | (Lester et al., 1980) (Chabala and Lester, 1986) |
| Tethered photoswitchable | Shaker K+/antagonist | (Chambers et al., 2006) |
| Tethered photoswitchable | nAChR/agonist and antagonist | (Tochitsky et al., 2012) (Damijonaitis et al., 2015) |
| Tethered photoswitchable | mGluR2/agonist and antagonist | (Levitz et al., 2013) |
| Tethered photoswitchable | D1R and D2R/agonist | (Donthamsetti et al., 2017) |
| Remotely tethered photoswitchable | mGluR2/agonist | (Broichhagen et al., 2015a). |
| Remotely tethered photoswitchable | mGluR6–8/agonist | (Levitz et al., 2017) |
| Remotely tethered photoswitchable (nanobody) | mGluR2/agonist | (Farrants et al., 2018) |
| Remotely tethered photoswitchable | mGluR2/agonist | (Acosta-Ruiz et al., 2020) (Gutzeit et al., 2021) |
| Remotely tethered photoswitchable | GPR55/agonist | (Tobias et al., 2021) |
| Remotely tethered photoswitchable | D1R /agonist | (Donthamsetti et al., 2021b) |
| Remotely tethered photoswitchable | 5HT2A/agonist | (Morstein et al., 2022) |