TABLE 5.
Summary of mutation detection in a mixed population of a UL54 mutant and wild-type CMV a
| Ratio (%) of wild-type:UL54 mutant | UL54 mutation | Predicted resistance |
|---|---|---|
| 50:50 | D301N | G/C |
| 75:25 | D301N | G/C |
| 80:20 | D301N | G/C |
| 85:15 | D301N | G/C |
| 90:10 | D301N | G/C |
Mutations present at a prevalence of ≥15% were considered significant and indicated as present. G, ganciclovir; C, cidofovir.