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. 2023 Oct 20;16:4763–4776. doi: 10.2147/JIR.S428425

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© 2023 Chen et al.

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(A) Pathogenesis of spinal cord injury. (B) Normal spinal cord tissue. (C) When a spinal cord injury occurs, the nerve parenchyma and glial structures are damaged, neutrophils, macrophages/microglia, lymphocytes, etc. infiltrate the injured area, and the concentration of compounds that aggravate spinal cord injury (inflammatory cytokines, reactive oxygen species, tissue-degrading enzymes, etc.) rises. (D) Formation of glial Scar.