TABLE 3.

Total kidney burdens of mice^a

Patient and isolate	Median total kidney burden (105 CFU/mouse) (range) of mice
	Control	Treated with FLUb
Patient 7
412	260 (79–800)	0.04c (0.01–3.1)
1907	230 (100–730)	4.4c (1.1–8)
2307	0.005 (<0.001–0.003)	0.0003 (<0.001–0.002)
Patient 14
580	24 (7.1–120)	0.8c (0.34–4.6)
649	5.5 (0.008–55)	2.3c (0.086–7.5)
2438	0.15 (0.44–120)	0.5 (0.11–4.1)
Patient 43
1649	6.6 (2–21)	0.03c (0.002–5.4)
1831	47 (27–170)	11c (1.8–29)
2183	57 (10–320)	3c (0.92–9.4)
Patient 9
437	4.9 (1.9–7.8)	0.03c (0.012–0.34)
1002	2.6 (1.3–10)	0.018c (0.009–0.06)
1442d	3.0 (0.6–9.6)	0.054c (0.015–10)
2271	11 (7.1–52)	0.022c (0.011–0.5)
2823	3.2 (0.7–51)	0.14c (0.09–0.8)
Patient 40
1622	9.9 (0.02–291)	0.01c (0.01–3.1)
2225	6.6 (0.8–609)	0.1c (0.03–0.7)
2512	10.4 (02.7–43)	0.07c (0.01–0.35)

^aTotal kidney burdens of mice on day 8 after intravenous infection of immune competent mice with 10⁶ CFU of C. albicans isolate per mouse. 

^bMice were treated with 5 mg of fluconazole (FLU) per kg. 

^cSignificantly different from the control value (P < 0.05). 

^dAn error was made for mice infected with isolate 1442; the infecting dose was 10⁷ CFU/mouse.