TABLE 3.

Susceptibility (μg/ml) of clinical isolates of S. pneumoniae, Haemophilus spp., and P. aeruginosa

Species and agent	MIC (μg/ml) of NCTC control strain	MIC (μg/ml)a
		50%	90%	Range
S. pneumoniae (n = 19)
Ciprofloxacin	0.5	1	32	2–32
Ciprofloxacin + reserpine	0.5	0.5	8	0.5–8
Sparfloxacin	0.25	0.5	16	0.03–32
Clinafloxacin	0.06	0.12	1	0.06–1
Gatifloxacin	0.5	0.25	4	0.03–8
Grepafloxacin	0.5	0.5	16	0.06–64
Levofloxacin	0.5	1	32	0.06–32
Moxifloxacin	0.5	0.25	4	0.06–4
Trovafloxacin	0.25	0.12	4	0.06–4
Haemophilus spp. (n = 5)
Ciprofloxacin	0.008			0.5–8
Sparfloxacin	0.008			0.5–8
Clinafloxacin	0.004			0.12–1
Gatifloxacin	0.06			0.25–2
Grepafloxacin	0.12			1–8
Levofloxacin	0.06			1–16
Moxifloxacin	0.06			1–4
Trovafloxacin	0.06			0.25–1
P. aeruginosa (n = 10)
Ciprofloxacin	1	2	8	0.25–8
Sparfloxacin	4	8	32	8–32
Clinafloxacin	1	1	4	0.06–4
Gatifloxacin	4	4	16	0.5–16
Grepafloxacin	8	8	32	0.5–32
Levofloxacin	1	4	16	0.5–16
Moxifloxacin	16	16	32	16–32
Trovafloxacin	0.5	4	32	0.5–32

^a50% and 90%, MICs at which 50 and 90% of the isolates are inhibited, respectively.