TABLE 1.
Drug | Mean IC50 (nM) ± SD for isolate:
|
|
---|---|---|
K1 | HB3 | |
Ro40-4388 | 256 ± 26 | 318 ± 22 |
E64 | 8,982 ± 744 | 9,653 ± 1,677 |
AQ | 18.3 ± 1.5 | 4.1 ± 1 |
CQ | 110 ± 10 | 17.7 ± 2.5 |
HF | 2.6 ± 0.9 | 3.8 ± 0.3 |
MQ | 14.8 ± 3.2 | 28.7 ± 3.5 |
QN | 176 ± 25 | 100 ± 20 |
PQ | 2,027 ± 635 | 8,086 ± 278 |
Data were derived from at least three assays performed at a hematocrit of 1% and a parasitemia of 1%.