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. 1998 Nov;42(11):2973–2977. doi: 10.1128/aac.42.11.2973

TABLE 1.

In vitro sensitivities of the K1 and HB3 isolates of P. falciparum to the selected antimalarial drugs and proteinase inhibitorsa

Drug Mean IC50 (nM) ± SD for isolate:
K1 HB3
Ro40-4388 256 ± 26 318 ± 22
E64 8,982 ± 744 9,653 ± 1,677
AQ 18.3 ± 1.5 4.1 ± 1
CQ 110 ± 10 17.7 ± 2.5
HF 2.6 ± 0.9 3.8 ± 0.3
MQ 14.8 ± 3.2 28.7 ± 3.5
QN 176 ± 25 100 ± 20
PQ 2,027 ± 635 8,086 ± 278
a

Data were derived from at least three assays performed at a hematocrit of 1% and a parasitemia of 1%.