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Effect of a C-8-Br group on bactericidal action of fluoroquinolones. M. bovis BCG strain KD1295 (wild type; open symbols) or strain CX1 (first-step gyrA mutant; filled symbols) was treated as in Fig. 2. Arrows indicate concentrations that are 4 times the ID50 for each compound. Symbols: circles, PD163753 (C-8-Br); squares, PD138032 (C-8-H).
