Table 3.

Examples for antibiotic treatment of an acute tonsillitis episode probably related to a GAS infection.

Group of patients	First choice	In the case of penicillin intolerance or second choice
Adolescents (>15 years) and adults	Penicillin V (phenoxymethylpenicillin-potassium 0.8–1.0 million IU (or phenoxymethylpenicillin benzathine 100.000 IU/kg body weight) orally three times daily for 5–7 days	Clarithromycin 250–500 mg orally twice daily for 5 days OR erythromycin 40 mg/kg body weight divided into 2 single oral doses for 5 days OR clindamycin (20 mg/kg body weight/day divided into three single oral doses for 5 days)
Children (3–15 years)	Penicillin V 0.05–0.1 million IU/kg body weight/day divided into three single oral doses for 5–7 days	Clarithromycin 15 mg/kg body weight/day divided into two single oral doses for 5 days.
Individual cases at increased risk for a severe course	Pathogen eradication with penicillin for 10 days