Table 5.

Effect of SeNPs on the biochemistry and hematology of broiler chickens.

Blood traits	T1	T2	T3	T4	T5
Liver enzymes
ALT	17.1 ± 0.2c	9.3 ± 0.6d	28.3 ± 0.6a	17.9 ± 0.3c	20.3 ± 0.6b
AST	59.2 ± 0.3c	38.5 ± 0.1d	81.2 ± 0.3a	60.2 ± 0.1c	68.1 ± 0.5b
Antioxidant enzymes
GSH	62.1 ± 0.2a	60.2 ± 0.3b	33.6 ± 0.9d	60.9 ± 0.1b	57.5 ± 0.2c
GPx	29.8 ± 0.1b	32.1 ± 0.5a	11.3 ± 0.8d	22.6 ± 0.5c	21.1 ± 0.1c
SOD	4.6 ± 0.2b	4.8 ± 0.1a	2.9 ± 0.4d	4.6 ± 0.4b	4.1 ± 0.6c
Stress components
MDA	18.7 ± 0.2d	19.2 ± 0.3d	45.9 ± 0.2a	21.6 ± 0.6c	25.7 ± 0.6b
NO	8.9 ± 0.1d	9.1 ± 0.1d	22.5 ± 0.5a	10.22 ± 0.1c	12.1 ± 0.8b
Serum biochemical
Protein (g/dL)	2.70 ± 0.1b	2.9 ± 0.9a	1.0 ± 0.0e	2.5 ± 0.1c	2.0 ± 0.1d
Albumin (g/dL)	1.36 ± 0.2b	1.5 ± 0.1a	1.1 ± 0.01d	1.41 ± 0.2ab	1.32 ± 0.2c
Globulin (g/dL)	1.30 ± 0.6c	1.43 ± 0.5a	0.95 ± 0.02d	1.39 ± 0.6b	1.31 ± 0.3c
A/G ratio	1.07 ± 0.5b	1.04 ± 0.7b	1.15 ± 0.01a	1.01 ± 0.4c	1.00 ± 0.1c
Lipids (mg/dL)	0.42 ± 0.4b	0.35 ± 0.5c	0.58 ± 0.05a	0.31 ± 0.06d	0.34 ± 0.04c
Hematological parameters
RBCs (106/µL)	2.4 ± 0.2bc	2.7 ± 0.3a	1.9 ± 0.2d	2.5 ± 0.1b	2.3 ± 0.2c
WBCs 102/µL)	138 ± 0.8b	130 ± 1.1c	145 ± 1.2a	131 ± 1.2c	136 ± 1.2bc
PLT (104/µL)	39.2 ± 0.8b	32.6 ± 0.6d	48.1 ± 0.2a	33.6 ± 0.6d	36.6 ± 0.2c

The values are presented as mean ± SE, lowercase letters (a–e) in each row indicate the significant differences between different treatments on the biochemistry and hematology of broiler chickens using LSD test at P < 0.05. T1: Non infected chicks; T2: Non infected chicks + SeNPs 500 mg/kg diet for 35 d; T3: E. tenella-infected chicks and non-treated; T4: E. tenella-infected chicks + treated with SeNPs 500 mg/kg; diet for 5 d; T5: E. tenella-infected chicks + treated with sulfadimidine, 16% solution 8 mL/L of drinking water for 5 d.