TABLE 2.

Lesion healing and virologic response

Group	No. of patients	Median time to complete healing (95% CIa; P value)			Median time (days) to virus shedding cessation (95% CI; P value)
		All patients	Females	Males	All patients	Females	Males
Placebo	32	5.0 (4–6)	5.3 (4–7)	4.9 (4–6)	3.0 (2–4)	2.6 (2–4)	3.2 (2–4)
1% cidofovir	20	4.3 (3–5; NSb)	4.3 (4–6; NS)	5.0 (3–6; NS)	2.2 (1–3; 0.02)	1.7 (1–2; NS)	2.9 (1–3; NS)
3% cidofovir	21	4.1 (4–5; NS)	3.8 (3–5; 0.04)	4.4 (4–6; NS)	1.3 (1–2; 0.0001)	1.3 (1–2; 0.004)	1.4 (1–2; 0.01)
5% cidofovir	23	4.6 (4–7; NS)	4.0 (4–7; NS)	6 (4–NRc; NS)	1.1 (1–2; 0.0007)	1.1 (1–2; 0.02)	1.1 (1–2; 0.01)
Combined cidofovir	64	4.2 (4–5; NS)	3.9 (4–5; NS)	4.7 (4–6; NS)	1.3 (1–2; 0.0001)	1.3 (1–2; 0.007)	1.4 (1–2; 0.003)

^aCI, confidence interval. 

^bNS, not significant. 

^cNR, not reached.