Table 3.
Simplified clinical screening model for gestational diabetes mellitus
| Clinical measures | Laboratory data in the first trimester | ||||
|---|---|---|---|---|---|
| Predictors | Categories | Score | Predictors | Categories | Score |
| Maternal age (years) | < 35 | 0 | FBG (mmol/L)b | < 5.1 | 0 |
| 35–40 | 2 | 5.1–5.6 | 2 | ||
| ≥ 40 | 4 | ≥ 5.6 | 4 | ||
| preBMI (kg/m2) | < 24 | 0 | ALT/AST ratio | < 0.825 | 0 |
| 24–28 | 10 | ≥ 0.825 | 5 | ||
| ≥ 28 | 20 | ||||
| Family history of diabetesa | None | 0 | TG/HDL-C ratio | < 0.676 | 0 |
| Yes | 1 | ≥ 0.676 | 3 | ||
GDM gestational diabetes mellitus, preBMI prepregnancy body mass index, FBG fasting blood glucose, ALT alanine transaminase, AST aspartate aminotransferase, TG triglyceride, HDL-C high-density lipoprotein cholesterol
aDefined as at least 1 family member having been diagnosed with diabetes
bParticipants with an FBG level ≥ 6.1 mmol/L in the first trimester were excluded from this prediction model because of probable impaired glucose intolerance before pregnancy