Table 7.
Correlation analysis between the gut phylum and inflammatory markers with fecal short-chain fatty acids in the studied groups.
| Grouping | Variables | Acetic acid | Propionic acid | Butyric acid |
|---|---|---|---|---|
| LCD | Actinobacteria | r = − 0.16; p = 0.5 | r = 0.45; p = 0.04 | r = − 0.02; p = 0.9 |
| Proteobacteria | r = 0.19; p = 0.4 | r = − 0.14; p = 0.6 | r = − 0.27; p = 0.27 | |
| hs-CRP | r = 0.29; p = 0.2 | r = 0.42; p = 0.08 | r = 0.02; p = 0.9 | |
| IL-6 | r = 0.02; p = 0.9 | r = 0.43; p = 0.01 | r = − 0.27; p = 0.2 | |
| HD | Actinobacteria | r = 0.38; p = 0.14 | r = 0.49; p = 0.05 | r = − 0.04; p = 0.9 |
| Proteobacteria | r = − 0.07; p = 0.8 | r = 0.42; p = 0.1 | r = 0.05; p = 0.8 | |
| hs-CRP | r = − 0.09; p = 0.7 | r = 0.08; p = 0.7 | r = 0.06; p = 0.8 | |
| IL-6 | r = 0.02; p = 0.9 | r = 0.08; p = 0.7 | r = 0.06; p = 0.8 | |
| LCD to HD | Actinobacteria | r = − 0.07; p = 0.8 | r = − 0.07; p = 0.8 | r = − 0.07; p = 0.8 |
| Proteobacteria | r = 0.36; p = 0.2 | r = 0.13; p = 0.65 | r = − 0.05; p = 0.8 | |
| hs-CRP | r = 0.3; p = 0.2 | r = 0.4; p = 0.15 | r = 0.37; p = 0.18 | |
| IL-6 | r = − 0.09; p = 0.7 | r = 0.04; p = 0.9 | r = − 0.3; p = 0.3 | |
| HD to LCD | Actinobacteria | r = − 0.3; p = 0.3 | r = − 0.15; p = 0.6 | r = − 0.08; p = 0.7 |
| Proteobacteria | r = 0.08; p = 0.78 | r = 0.6; p = 0.02 | r = 0.25; p = 0.4 | |
| hs-CRP | r = 0.06; p = 0.8 | r = 0.36; p = 0.2 | r = − 0.12; p = 0.7 | |
| IL-6 | r = − 0.3; p = 0.25 | r = − 0.06; p = 0.8 | r = − 0.3; p = 0.27 |
Correlation analysis was performed by the Kendall’s tau-b and Spearman test. The bold values are significant.
LCD low-carbohydrate diet; HD habitual diet; LCD to HD low-carbohydrate diet to habitual diet; HD to LCD habitual diet to low-carbohydrate diet; each diet for six weeks with two weeks washout period; IL-6 interleukin-6; hs-CRP high sensitive C-reactive protein.