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. 2023 Oct 24;9:394. doi: 10.1038/s41420-023-01690-w

Fig. 8. Exogenous H2S prevents apoptosis by regulating Syvn1-mediated ubiquitination of Keap1.

Fig. 8

A, B Sulfhydration levels of Syvn1 (S-Syvn1) in (A) cardiac tissues and in (B) HL-1 cardiomyocytes. C Expression of GPx4 in HL-1 cardiomyocytes, n = 3. D Cytoplasmic and mitochondrial Cyt c levels in HL-1 cardiomyocytes, n = 3. E Cell death determined by PI/Hoechst staining, n = 3. Scale bar: 100 μm. All quantitative data are presented as mean ± SD from independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001 by ordinary one-way ANOVA.