Fig. 6. Spatial patterns at the individual level.

a Regional structure-function coupling estimated by low-frequency eigenmodes for every region and subject. b The corresponding brain map where nodes are colored from blue to red in increasing order of R values. c Regional structure-function coupling grouped by 7 brain functional systems. Each point represents a brain region (n = 1000 regions). Boxplots are contained within violinplots, where the white circle denotes the median, the box denotes the interquartile range, and the whiskers denote the upper/lower bounds of 1.5 $\times$ the interquartile range. The network-specific mean R was then compared with the null distribution generated by spatially constrained permutation (10,000 repetitions). * indicates the empirical P < 10⁻⁴ (two-sided, FDR corrected). d Regional structure-function coupling estimated by high-frequency eigenmodes for every region and subject. e The corresponding brain map where nodes are colored from blue to red in increasing order of R values. f Regional structure-function coupling grouped by 7 brain functional systems. Each point represents a brain region (n = 1000 regions). Boxplots are contained within violinplots, where the white circle denotes the median, the box denotes the interquartile range, and the whiskers denote the upper/lower bounds of 1.5 $\times$ the interquartile range. The network-specific mean R was then compared with the null distribution generated by spatially constrained permutation (10,000 repetitions). * indicates the empirical P < 10⁻⁴ (two-sided, FDR corrected). Source data are provided as a Source Data file.