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. 2023 Oct 24;13:18197. doi: 10.1038/s41598-023-45132-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Methylome analyses of ASD and CTRL groups. Principal Component Analysis plots of DNA methylation profiles showing cluster of sample groups (in orange, CTRL group (N = 7); in green ASD group (N = 8)) based on the quality filtered CpG sites (A), promoters (B) and genes (C). Hierarchical cluster analyses based on DNA methylation levels at 1000 most variable CpG sites (D), promoters (E) and genes (F).