Table 4.
Validity and reliability of DECT and MRI for the diagnosis of ACL rupture
| DECT | MRI | |||||
|---|---|---|---|---|---|---|
| Reader 1 | Reader 2 | Overall | Reader 1 | Reader 2 | Overall | |
| Sensitivity (%)† |
98.0 (50/51) [82.8–100.0] |
96.1 (49/51) [79.8–99.9] |
97.1 (99/102) [88.1–99.8] |
100 (51/51) [86.3–100.0] |
98.0 (50/51) [82.8–100.0] |
99.0 (101/102) [91.2–100.0] |
| Specificity (%)† |
98.0 (50/51) [82.8–100.0] |
98.0 (50/51) [82.8–100.0] |
98.0 (100/102) [89.5–99.9] |
100 (51/51) [86.3–100.0] |
100 (51/51) [86.3–100.0] |
100 (102/102) [93.0–100.0] |
| PPV (%)† |
98.0 (50/51) [89.5–99.9] |
98.0 (49/50) [89.4–99.9] |
98.0 (99/101) [93.0–99.8] |
100 (51/51) [93.0–100.0] |
100 (50/50) [92.9–100.0] |
100 (101/101) [96.4–100.0] |
| NPV (%)† |
98.0 (50/51) [89.5–99.9] |
96.2 (50/52) [86.9–99.5] |
97.1 (100/103) [91.7–99.4] |
100 (51/51) [93.0–100.0] |
98.1 (51/52) [89.8–100.0] |
99.0 (102/103) [94.7–100.0] |
| LR+ | 50.0 | 49.0 | 49.5 | ∞ | ∞ | ∞ |
| LR− | 0.02 | 0.04 | 0.03 | 0.00 | 0.02 | 0.01 |
| AUC (%)† | ||||||
| 80-keV CT value | 98.0 [97.0–98.9] | – | ||||
| Mixed-keV CT value | 99.2 [98.6–99.7] | – | ||||
| Rho | 99.8 [99.6–100.0] | – | ||||
| Zeff | n.s | |||||
| Accuracy (%)† |
98.0 (100/102) [93.0–99.7] |
97.1 (99/102) [91.7–99.4] |
97.5 (199/204) [94.3–99.2] |
100 (102/102) [96.4–100.0] |
99.0 (101/102) [94.6–100.0] |
99.5 (203/204) [97.3–100.0] |
| p value‡ | > 0.99 | |||||
PPV, positive predictive value; NPV, negative predictive value; LR+, positive likelihood ratio; LR−, negative likelihood ratio; AUC, area under the curve
†Data expressed as percentages, with raw data in parentheses and 95% CIs in brackets
‡p value was obtained using McNemar’s test for the comparison of diagnostic performance between MRI and DECT