Table 2.
Spearman correlation coefficients (rS) and corresponding two-sided p values (p) for pre- and post-NACT measurements of tumour burden versus blood biomarkers measured at baseline
Pre-chemotherapy | |||||||||
---|---|---|---|---|---|---|---|---|---|
Oment. vol. | Pelvis/ovaries vol. | LN vol. | Total vol. | Number lesions | Summed diameter | Ascites | Pleural effusion | ||
Baseline TP53 MAF | rS | 0.04 | 0.37 | 0.26 | 0.37 | 0.32 | 0.48 | 0.05 | 0.13 |
p | 0.77 | 0.005 | 0.06 | 0.005 | 0.02 | 0.0003 | 0.77 | 0.36 | |
Baseline CA-125 | rS | 0.41 | 0.38 | 0.21 | 0.48 | 0.28 | 0.45 | 0.28 | 0.23 |
p | 0.002 | 0.005 | 0.13 | 0.0003 | 0.04 | 0.0009 | 0.04 | 0.10 |
Post-chemotherapy | |||||||||
---|---|---|---|---|---|---|---|---|---|
Oment. vol. | Pelvis/ovaries vol. | LN vol. | Total vol. | Number lesions | Summed diameter | Ascites | Pleural effusion | ||
Baseline TP53 MAF | rS | −0.04 | 0.30 | 0.13 | 0.29 | 0.19 | 0.41 | 0.03 | 0.13 |
p | 0.79 | 0.03 | 0.36 | 0.03 | 0.17 | 0.003 | 0.79 | 0.36 | |
Baseline CA-125 | rS | 0.10 | 0.23 | 0.10 | 0.22 | 0.20 | 0.32 | −0.07 | −0.16 |
p | 0.50 | 0.10 | 0.50 | 0.11 | 0.15 | 0.02 | 0.63 | 0.24 |
p values are adjusted for multiple correction.
Significant correlations (p < 0.05) are highlighted in bold.