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. 2022 Jun 20;12(5):658–670. doi: 10.21037/hbsn-21-520

Table 1. Comparison of primary endpoints between restrictive procedures and foregut bypass.

Grade Restrictive procedures Foregut bypass Subgroup difference
No. of studies OR (95% CI) Cochran Q I2 P value No. of studies OR (95% CI) Cochran Q I2 P value
F0/F1 4 4.55 (1.42 to 14.55) 0.3 18.60% 0.03* 10 3.23 (1.80 to 5.79) 0.81 0.00% <0.01* 0.44
S0 4 14.42 (1.35 to 153.57) 0.03 65.60% 0.04* 10 75.40 (31.17 to 182.41) 0.37 8.30% <0.01* 0.05*
I0 3 6.25 (1.27 to 30.81) 0.4 0.00% 0.04* 8 15.99 (5.65 to 45.27) 0.25 22.10% <0.01* 0.10
B0 2 27.44 (0.00 to 70.13) 0.04 75.60% 0.27 6 17.17 (6.25 to 47.15) 0.54 0.00% <0.01* 0.77

*, P value ≤0.05 denotes statistical significance. F0/F1 represents reversal of clinically significant fibrosis; S0, I0, and B0 represents resolution of steatosis, lobular inflammation, and ballooning respectively. OR, odds ratio; CI, confidence interval.