Table 2. Modified Igls classification after islet auto-transplantation.
| Classification | HbA1c | SHE (per year) | Insulin dose | C-peptide |
|---|---|---|---|---|
| (A) Igls | ||||
| Optimal | <6.5% | None | None | > Baseline |
| Good | <7% | None | <50% Baseline | > Baseline |
| Marginal | Baseline | < Baseline | ≥50% Baseline | > Baseline |
| Failed | Baseline | Baseline | Baseline | Baseline |
| (B) Minnesota Auto-Igls | * | |||
| Optimal | <6.5% | None | None | >0.5 ng/mL (≥0.2 ng/mL) |
| Good | <7% | None | <0.5 units/kg/day | >0.5 ng/mL (≥0.2 ng/mL) |
| Marginal | ≥7% | ≥1 | ≥0.5 units/kg/day | >0.5 ng/mL (≥0.2 ng/mL) |
| Failed | – | – | – | ≤0.5 ng/mL (≥0.2 ng/mL) |
| (C) Leicester Auto-Igls | * | |||
| Good | – | – | None (up to 5 years) | >0.5 ng/mL (≥0.2 ng/mL) |
| Partial | – | – | <20 units/day | >0.5 ng/mL (≥0.2 ng/mL) |
| Poor | – | – | 20–40 units/day (within 5 years) | >0.5 ng/mL (≥0.2 ng/mL) |
| Failed | – | – | – | ≤0.5 ng/mL |
*, C-peptide stimulated (fasting). (A) Original Igls classification; (B) Minnesota Modified Auto-Igls classification; (C) Leicester Modified Auto-Igls classification. HbA1c, haemoglobin A1c; SHE, severe hypoglycaemia episodes.