Skip to main content
. Author manuscript; available in PMC: 2023 Oct 25.
Published in final edited form as: Nat Rev Neurosci. 2023 Jan 25;24(4):195–212. doi: 10.1038/s41583-022-00674-6

Fig. 5 |. Major phenotypes in humans with spectrinopathies of the nervous system.

Fig. 5 |

Pathogenic variants in spectrins cause complex neurological syndromes in both the brain and periphery that have overlapping pathologies and clinical presentations across spectrin genes. Affected spectrin genes indicated in parentheses. ADHD, attention deficit hyperactivity disorder; ASD, autism spectrum disorder; DD, developmental delay; ID, intellectual disability.