aHUS |
atypical hemolytic uremic syndrome |
AKT |
protein kinase B |
AMD |
age-related macular degeneration |
BrM |
Bruch’s membrane |
C4BP |
C4b-binding protein |
CCPs |
complement control protein |
COC |
cumulus oophorous complex |
CRP |
C reactive protein |
Cryo-EM |
cryogenic electron microscopy |
DAMPs |
danger-associated molecular patterns |
DC-SIGN |
dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin |
ECM |
extracellular matrix |
ERK1/2 |
extracellular signal-regulated kinase 1/2 |
FAK |
focal adhesion kinase |
fB |
factor B |
FG |
fibrinogen/fibrin |
FGFs |
fibroblast growth factors |
fH |
factor H |
FHL-1 |
factor H-like protein 1 |
FHR-1 & -5 |
factor H-related protein 1 & 5 |
HA |
hyaluronic acid |
HCs |
heavy chains |
IL-1β |
interleukin-1β |
IαI |
inter-alfa-trypsin inhibitor |
LPS |
lipopolysaccharide |
MBL |
mannose binding lectin |
NF‐κB |
nuclear factor kappa-B |
NPTX1 or NP1 |
neuronal pentraxins 1 |
NPTX2 or Narp or NP2 |
neuronal pentraxins 2 |
NPTXR |
neuronal pentraxin receptor |
oBRB |
outer blood-retinal barrier |
OmpA |
outer membrane protein A |
OMV |
outer membrane vesicles |
PAMPs |
pathogen-associated molecular patterns |
PG |
plasminogen |
PRMs |
pattern recognition molecules |
PTX3 |
pentraxin 3 |
PTX4 |
pentraxin 4 |
RPE |
retinal pigment epithelium |
SAP |
serum amyloid P component |
SARS_COV_2 |
severe acute respiratory syndrome coronavirus 2 |
TNF-α |
tumor necrosis factor-α |
TSG-6 |
tumor necrosis factor-inducible gene 6 protein |
TSP1 |
thrombospondin 1 |