Figure 5.

Posterior parameter distributions of the calibrated digital twins after assimilating observed data at the three imaging visits are shown for three patients: (A) Patient 1, (B) Patient 2, and (C) Patient 3. The dashed gray line indicates true parameter values for reference and not seen by the digital twin. Note that the same prior distribution is used for initializing digital twins of all the patients. Posterior distributions concentrate around the unseen true parameters and show reduction in uncertainty compared to prior distributions.