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Physical state model parameters θtrue for simulating in silico case-study patients.
| Model parameter | Patient 1 | Patient 2 | Patient 3 |
|---|---|---|---|
| Proliferation rate ρ (day−1) | 1.14e-01 | 1.09e-01 | 2.25e-01 |
| Carrying capacity K (cells) | 1.17e+11 | 1.09e+11 | 1.40e+11 |
| Initial tumor burden Ninitial (cells) | 1.54e+10 | 2.60e+10 | 2.62e+10 |
| Radiosensitivity parameter α (Gy−1) | 1.05e-03 | 4.58e-02 | 3.90e-02 |
| Chemotherapy surviving fraction SC | 0.82 | ||
| Radiosensitivity parameter ratio α/β (Gy) | 10 | ||
