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. 2023 Sep 30;102(12):103155. doi: 10.1016/j.psj.2023.103155

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© 2023 Published by Elsevier Inc. on behalf of Poultry Science Association Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Effects of saikosaponin a treatment on the relative mRNA expression in the ileal (A) and liver (B) of laying hens (n = 6). ^a,bDifferent letters represent significant differences (P < 0.05). CON, control group; HELP, high-energy and low-protein diet group; HELP + SSa, high-energy and low-protein with saikosaponin a group; LXRα: liver X receptor α; FXR: farnesoid X receptor; FGF: fibroblast growth factor; CYP7a: cholesterol 7α-hydroxylase; ACC: acetyl-CoA carboxylase; FAS: fatty acid synthetase; SREBP: sterol-regulatory element-binding protein; PPAR: peroxisome proliferator-activated receptor; HMGCR: β-hydroxy-β-methylglutaryl-coenzyme reductase; ASBT: apical sodium-dependent bile acid transporter; Ibabp: ileum bile acid binding protein.