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Tubulin polymerization inhibition screening results showing the active virtual hits at 30 μM (SC6, SC22, SC23, SC25, SC27, SC32, SC34, SC37, and colchicine 1a), 20 μM (SC24), and 10 μM (SC14). Results expressed at time point 41.5 min as % inhibition of blank (mean ± SD, n = 2) and compared to control (1a) and blank. Statistical significance compared to blank analyzed by t test: *p < 0.05, **p < 0.01, n.s = not significant.
