Table 1. Theoretical Evaluation of LS and DS Generated Models^a.

Model	Actives	Decoy	TPs	FPs	TNs	FNs	Accuracy	Sensitivity	Specificity	YoA	EF
SB1	7	49	7	49	4852	88	0.97	0.07	0.99	0.13	6.57
SB2	6	69	6	69	4832	89	0.97	0.06	0.99	0.08	4.21
LB3	12	51	12	51	4850	83	0.97	0.13	0.99	0.19	10.02
LB4	8	15	8	15	4886	87	0.98	0.08	1.00	0.35	18.29
LB5	13	16	13	16	4885	82	0.98	0.14	1.00	0.45	23.57
LB6	5	24	5	24	4877	90	0.98	0.05	1.00	0.17	9.07
LB7	4	32	4	32	4869	91	0.98	0.04	0.99	0.11	5.84
LB8	3	18	3	18	4883	92	0.98	0.03	1.00	0.14	7.51
LB9	5	52	5	52	4849	90	0.97	0.05	0.99	0.09	4.61
LB10	5	58	5	58	4843	90	0.97	0.05	0.99	0.08	4.17
LB11	9	45	9	45	4856	86	0.97	0.09	0.99	0.17	8.76
DS2	10	49	10	49	4852	85	0.97	0.11	0.99	0.17	8.91
DS5	11	57	11	57	4844	84	0.97	0.12	0.99	0.16	8.51
DS8	10	74	10	74	4827	85	0.97	0.11	0.98	0.12	6.26
DS9	9	64	9	64	4837	86	0.97	0.09	0.99	0.12	6.48
DS12	15	86	15	86	4815	80	0.97	0.16	0.98	0.15	7.81
Combined	89	677	89	677	4224	6	0.86	0.94	0.86	0.12	6.11

^aEach model was evaluated in relation to EF, YoA, and number of TPs.