TABLE 1.
Transcript variant | Synonyms | Isoform | Nt a | AA b | CCDS c | |
---|---|---|---|---|---|---|
1 | SIN1 | 1.1 | 3369 | 522 | Canonical isoform | CCDS35140.1 |
2 | SIN1 beta | 1.2 | 1461 | 486 | Lacks an alternate in‐frame exon in the 3′ coding region, compared to variant 1. | CCDS6864.1 |
3 | SIN1 gamma | 1.3 | 1428 | 475 | Lacks an alternate in‐frame exon in the 3′ coding region, compared to variant 1 | CCDS35139.1 |
4 | SIN1 delta | 1.4 | 993 | 330 | Has a shorter N‐terminus, compared to isoform 1. The existence of this isoform has not been confirmed experimentally. Variants 4 and 5 encode the same isoform. | CCDS35141.1 |
5 | SIN1 epsilon | 1.4 | 993 | 330 | Also known as SIN1e, lacks two alternate in‐frame exons in the 5′ coding region, and uses a downstream start codon, compared to variant 1. The resulting protein (isoform 4), also known as the delta isoform, has a shorter N‐terminus, compared to isoform 1. The existence of this isoform has not been confirmed experimentally. Variants 4 and 5 encode the same isoform. | CCDS35141.1 |
6 | SIN1 alpha | 1.5 | 972 | 323 | Differs in the 3′ coding region and UTR, compared to variant 1 | CCDS48020.1 |
number of nucleotides.
Amino Acid.
Consensus Coding Sequence.