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. 2023 Oct 25;13(10):e1464. doi: 10.1002/ctm2.1464

TABLE 1.

Transcript variant and isoform of SIN1.

Transcript variant Synonyms Isoform Nt a AA b CCDS c
1 SIN1 1.1 3369 522 Canonical isoform CCDS35140.1
2 SIN1 beta 1.2 1461 486 Lacks an alternate in‐frame exon in the 3′ coding region, compared to variant 1. CCDS6864.1
3 SIN1 gamma 1.3 1428 475 Lacks an alternate in‐frame exon in the 3′ coding region, compared to variant 1 CCDS35139.1
4 SIN1 delta 1.4 993 330 Has a shorter N‐terminus, compared to isoform 1. The existence of this isoform has not been confirmed experimentally. Variants 4 and 5 encode the same isoform. CCDS35141.1
5 SIN1 epsilon 1.4 993 330 Also known as SIN1e, lacks two alternate in‐frame exons in the 5′ coding region, and uses a downstream start codon, compared to variant 1. The resulting protein (isoform 4), also known as the delta isoform, has a shorter N‐terminus, compared to isoform 1. The existence of this isoform has not been confirmed experimentally. Variants 4 and 5 encode the same isoform. CCDS35141.1
6 SIN1 alpha 1.5 972 323 Differs in the 3′ coding region and UTR, compared to variant 1 CCDS48020.1
a

number of nucleotides.

b

Amino Acid.

c

Consensus Coding Sequence.